Updated August 12, 2017 at 3:23 PM
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Small dog alert! Small dogs are more likely to experience adverse reactions, and shots containing multiple vaccines are more likely to cause adverse reactions according to renowned pet vaccine expert Dr. Jean Dodds. Melissa Kennedy, DVM, PhD, DACVIM wrote in DVM360 on-line magazine: "The likelihood ofadverse reactions in dogs has been found to correlate with the size of the dog and the number of inoculations given, with higher risk associated with small size and multiple inoculations." This means: no combo shots for small dogs -- or any other dogs for that matter. And NEVER GIVE ANY OTHER SHOT WITH A RABIES SHOT. Wait at least three or four weeks between the rabies shot and other shots.