Updated August 12, 2017 at 3:23 PM

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Signs of Cystinuria usually include blood in the urine, difficulty and pain in urinating, and small frequent amounts of urine. If a stone completely obstructs the urethra and thus blocks the outflow of urine (more common in male dogs) this may cause kidney failure - vomiting, depression, loss of appetite.Treating of cystinuria requires individual approach and lifelong treatment. In most cases special diets and increased water intake are recommended along with medications and surgery to dissolute or remove stones.

 Recent studies show that cystinuria may be #1 risk factor for developing taurine deficiency in dogs. A deficiency of taurine (taurine is a product of taurocholic acid involved in emulcification of fats and occurring in the bile) can cause blindness and heart disease. Low-quality commercial foods are usually deficient in taurine.Mitral Valve DiseaseThis term encompasses many heart diseases involving degenerative thickening and progressive deformity of one or more heart valves - mitral valve disease, mitral valve degeneration, mitral valve insufficiency etc. Mitral valve disease is a serious heart condition caused by the abnormal function of the valve that separates the upper and lower chamber of the left side of the heart. This disease is usually associated with heart murmur that can be heard with a stethoscope. It commonly affects Miniature Schnauzers, Chihuahuas, Fox Terriers, Cocker Spaniels, Cairn Terriers, Miniature Poodles, Bull Terriers, Boston Terriers, King Charles Spaniels, Miniature Pinschers, Dachshunds, Doberman Pinschers and Shetland Sheepdogs. Males are 50 percent more likely than females to be affected.The diseases may result from congenital defect of the valve, defects in the muscles and tendons that operate the valve, or inflammation of the heart. The disease usually occurs in older dogs; however it is seen in young dogs and may result in premature death. Symptoms may include exercise intolerance, weakness, syncope (passing out), coughing at night or at rest because of a build-up of fluid in the lungs, shortness of breath, and lethargy.

​Mildly affected dogs can have a good quality of life for years. It all depends on when the diagnosis is made and when therapy is applied. There are many dogs with degenerative mitral disease that never progress to heart failure. While the prognosis for dogs with mitral valve disease at advanced stage is poor, some dogs may be managed with medications and low-sodium diet for a period that varies from case to case. There is no prevention for mitral valve disease. Early detection and appropriate treatment of the disease may improve the prognosis. HemophiliaHemophilia is a genetically inherited bleeding disorder caused by a deficiency of the blood clotting factors VIII (hemophilia A) or IX (hemophilia B).

​Classical hemophilia, hemophilia A, is the most common coagulation disorder in dogs.Signs of Severe HemophiliaSigns of severe hemophilia usually include excessive bleeding from the gums, when getting adult teeth, and areas of bleeding under the skin in the regions of hind legs, the knee joint as well as the chest or abdomen (part of the body that encloses the stomach, intestines, liver and pancreas), forehead and he shoulder area, cough and lameness. Treatment may include periodic blood transfusions.The prognosis for dogs with severe hemophilia is poor since it usually results in lethal complications of the bleeding in the central nervous system. Dogs with a mild to moderate deficiency of the blood clotting factor, may survive to adulthood without showing signs severe enough to require veterinary attention.